在肿瘤介入化学药物治疗中，药物主要作用于肿瘤部位，全身毒副作用小，但恶心、呕吐仍是最常见的。有效地控制恶心、呕吐对于保证化疗顺利完成具有重要意义。枢丹是高度选择性５－ＨＴ３受体拮抗剂，我科对枢丹介入化疗进行了临床观察，现总结如下。１　临床资料和方法１．１ In the intervention of chemotherapy in the treatment of cancer, the drug mainly acts on the tumor site, and the systemic side effects are small, but nausea and vomiting are still the most common. Effective control of nausea and vomiting is of great importance for ensuring the successful completion of chemotherapy. Guandan is a highly selective 5-HT3 receptor antagonist. Our department has conducted clinical observations on interventional chemotherapy for chemotherapies, which are summarized below. 1 Clinical data and methods 1.1