Plant gene editing, which can produce targeted modifications in plants, shows great potential for gene function analysis and precision breeding of crops[1].To produce gene-edited plants, gene editing reagents[2] (for example,CRISPR/Cas9 components) need to be delivered to plant cells.This involves a lengthy, costly and labor-intensive tissue culture step, which, moreover, is currently only possible in limited number of plant species, making it a major bottleneck in plant gene editing.In the recent issue of Nature Biotechnology, a research team from the University of Minnesota led by Daniel F.Voytas, describes a new method that produces gene-edited plants while sidestepping the need for tissue culture (Fig.1)[3].The method takes advantage of the de novo induction of meristems.