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目的:研究缺血性脑卒中患者急性期c反应蛋白(CRP)水平与病情及预后的相关性分析。方法:测定87例缺血性脑卒中患者发病后24h内的血清CRP水平,分析其与其他血生化指标危险因素及患者出院时的Barthel指数的关系。结果:CRP异常组冠心病患病率为50.98%、低密度脂蛋白胆固醇水平为(4.50±0.71)mmol/L,明显高于CRP正常组的27.78%(3.95±0.84 mmol/L(P<0.05)。CRP异常组出院时的Barthel指数(51.82±10.56)低于CRP正常组(62.36±8.02)(P<0.05)。CRP水平与Barthel指数间的相关性有统计学意义(r=0.741,P<0.001)。结论:缺血性脑卒中患者CRP水平对近期预后有预测作用。
Objective: To study the correlation between the level of c-reactive protein (CRP) and the severity and prognosis of patients with ischemic stroke. Methods: Serum CRP levels were measured in 87 patients with ischemic stroke within 24 hours after onset, and their relationship with risk factors of other blood biochemical parameters and Barthel index at discharge were analyzed. Results: The prevalence of coronary heart disease was 50.98% and low density lipoprotein cholesterol was (4.50 ± 0.71) mmol / L in CRP abnormal group, which was significantly higher than that in CRP normal group (27.78%, 3.95 ± 0.84 mmol / L, P <0.05 ) .The Barthel index (51.82 ± 10.56) in the abnormal CRP group was lower than that of the CRP normal group (62.36 ± 8.02) (P <0.05) .The correlation between the CRP level and the Barthel index was statistically significant (r = 0.741, P <0.001) .Conclusion: The level of CRP in ischemic stroke patients has a predictive effect on the short-term prognosis.