The true stress—strain curves and processing window of Ti-47Al-2Cr-1Nb were set up through thermal physical simulation. A method for refinement of the as-cast+HIPped structure was submitted, which included two-step deformation with a short intermediate heat-treatment between double deformations. The break-down operation of the canned ingot was performed by the isothermal forging processing mentioned above. The refining mechanism is characterized as breaking and bending of the as-cast+HIPped lamellae, dynamic recrystallization, and static globularization. Thus, a uniform and refined billet microstructure is obtained for the final component by forging operation. The deformation of a model disc is accomplished by the subsequent single-step isothermal forging at 1 100(1 150 ℃) using a closed compression die. The true stress-strain curves and processing window of Ti-47Al-2Cr-1Nb were set up through thermal physical simulation. A method for refinement of as-cast + HIPped structure was submitted, which included two-step deformation with a short intermediate The break-down operation of the canned ingot was performed by the isothermal forging processing mentioned above. The refining mechanism is characterized as breaking and bending of the as-cast + HIPped lamellae, dynamic recrystallization, and static globularization The deformation of a model disc is accomplished by the subsequent single-step isothermal forging at 1 100 (1 150 ° C) using a closed compression die.