自从链霉素、对氨柳酸钠,特别是异烟肼被广泛应用于临床以来,结核性脑膜炎(以下简称结脑)的存活率有了显著的提高,激素的应用使预后更有所改善。在应用有效的抗痨药物的基础上,辅助以激素,可以提高疗效,降低死亡率,减少后遗症的发生。激素有消炎、抗变态反应、抗纤维素形成作用,因而能消除渗出物,防止纤维素沉着粘连等。所以激素加化疗不但能减轻结核中毒症状,并可降低颅内压,改善脑膜刺激症状,尚能使抗痨药物更好地弥散。范永琛等在《儿童结核性脑膜炎》一文中指出,结脑患儿在治疗开始时常表现为病情加重或于短期内死亡,这可能是抗结核药物使大量的结核菌死亡,放出大量的结核 Since streptomycin, sodium salicylate, especially isoniazid is widely used clinically, the survival rate of tuberculous meningitis (hereinafter referred to as tuberculous meningitis) has been significantly improved, and the use of hormones to make the prognosis more improve. In the application of effective anti-tuberculosis drugs, based on the auxiliary hormone, can improve the curative effect, reduce mortality, reduce the occurrence of sequelae. Hormone anti-inflammatory, anti-allergic reaction, the role of anti-cellulose formation, which can eliminate exudate, prevent cellulite adhesion and so on. Therefore, hormone therapy can not only reduce the symptoms of tuberculosis poisoning, and can reduce intracranial pressure, improve meningeal irritation, still can make better dispersion of anti-tuberculosis drugs. Fan Yongchen et al in “children with tuberculous meningitis,” a article pointed out that children with tuberculosis at the beginning of the treatment often showed aggravating illness or death in the short term, which may be a large number of tuberculosis death of anti-TB drugs, release a large number of tuberculosis