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目的主要对原发性甲状腺功能亢进性肝损害临床相关因素及其治疗措施进行探讨。方法选取我院进行救治的甲亢患者126例,并对其临床资料进行回顾性分析,比较各年龄段甲亢患者发生肝损害的几率,并采取药物和手术两种治疗措施,分析其治疗效果。结果所有患者ALT、AST、TBI或(和)DBI、AKP、Y-GY均有不同程度的升高,但随甲亢病情的缓解而逐渐恢复,行相关治疗,均可在3~4个月内恢复肝功能。结论甲状腺功能亢进性肝损害发生的几率与患者年龄以及甲亢病程呈正相关的关系,一旦发现甲亢,应及早进行甲状腺以及护肝治疗。
Objective To investigate the clinical factors related to primary hyperthyroidism and its treatment. Methods Totally 126 hyperthyroidism patients were treated in our hospital. The clinical data of the patients were retrospectively analyzed. The incidence of liver damage in hyperthyroidism patients of all ages was compared. Two kinds of treatment measures were taken to analyze the therapeutic effect. Results All patients had ALT, AST, TBI or (and) DBI, AKP, Y-GY increased in varying degrees, but gradually recovered with the relief of hyperthyroidism, the relevant treatment can be within 3 to 4 months Restore liver function. Conclusions The incidence of hyperthyroidism liver damage is positively correlated with the age of patients and the course of hyperthyroidism. Once hyperthyroidism is found, thyroid and liver protection should be treated as soon as possible.