咳嗽和呼吸道分泌物排出困难是支气管哮喘的常见临床特点。虽然哮喘病人每天排痰量平均不超过25ml,但患者呼吸道内的粘液量是增加的。粘液堵塞所导致的空气停滞或肺不张并不少见;在哮喘持续状态(status asthma-tcus)的死者,气道内可见广泛的粘液堵塞。因此,使人推测可能存在粘膜纤毛功能受损。本文论证哮喘病人粘膜纤毛功能的紊乱,并讨论其病原学和药物治疗。呼吸粘膜的正常结构和功能从气管到终末细支气管的粘膜复盖着从柱状细胞管腔面突 Cough and discharge of respiratory secretions are common clinical features of bronchial asthma. Although asthma patients do not expect an average of more than 25 ml of sputum per day, the amount of mucus in the patient’s respiratory tract is increased. It is not uncommon for air stasis or atelectasis due to blockage of mucus; extensive blockage of mucus is visible in the airways in the dead of asthma-status. Therefore, it is speculated that there may be impaired mucociliary function. This article demonstrates the mucosal ciliary dysfunction in asthmatic patients and discusses its etiology and drug therapy. The normal structure and function of the respiratory mucosa from the trachea to the end of bronchiolar mucosa covered with a sudden from the columnar lumen surface sudden