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目的：探讨结肠癌、胃癌患者贫血的发病原因。方法：常规法系统地测定结肠癌、胃癌患者全血血红蛋白（Ｈｂ）、血浆游离Ｈｂ的浓度；全血铁、血浆铁含量；红细胞形态、计数；红细胞压积、红细胞渗透脆性试验、红细胞孵育渗透脆性试验；血浆蛋白质质和量的变化。并以正常人的血、血浆为对照。结果：全血血红蛋白、血浆铁、全血铁含量，红细胞计数、压积、血浆总蛋白、血浆白蛋白，癌症患者显著低于正常对照组。而血浆游离血红蛋白浓度，红细胞渗透脆性试验ＮａＣｌ浓度、红细胞孵育渗透脆性试验ＮａＣｌ－磷酸盐缓冲液浓度，癌症患者显著高于正常对照组。结论：各种癌症患者都有不同程度的贫血，原因是红细胞破坏太多、生成减少，癌肿溃烂出血。
Objective: To investigate the causes of anemia in patients with colon cancer and gastric cancer. Methods: Routinely and systematically determined the concentrations of whole blood hemoglobin (Hb) and plasma free Hb in patients with colon cancer and gastric cancer; whole body iron and plasma iron content; red blood cell morphology and count; hematocrit, erythrocyte osmotic fragility test, and red cell incubation and infiltration Brittleness test; changes in plasma protein content and quantity. And normal blood and plasma controls. RESULTS: Whole blood hemoglobin, plasma iron, whole blood iron content, red blood cell count, total pressure, plasma total protein, plasma albumin, and cancer patients were significantly lower than the normal control group. The plasma free hemoglobin concentration, erythrocyte osmotic fragility test NaCl concentration, erythrocyte incubation osmotic fragility test NaCl-phosphate buffer concentration, cancer patients were significantly higher than the normal control group. Conclusion: All kinds of cancer patients have varying degrees of anaemia due to too much red blood cell destruction, reduced production, and cancerous ulceration and bleeding.