重度子痫前期(severe preeclampsia,SE)是严重危害母婴健康和安全的产科并发症,是孕妇和围生儿死亡的主要原因之一[1]。至今,对其发病原因及致病机制仍缺乏系统全面统一的认识。近年来,学者们从细胞凋亡的角度来探讨妊娠期高血压疾病的病因和发病机制,为其预防和临床治疗寻找新 Severe preeclampsia (SE) is one of the main causes of maternal and perinatal mortality, which is an obstetric complication of severe maternal and child health and safety [1]. So far, its pathogenesis and pathogenesis is still lack of systematic and comprehensive understanding. In recent years, scholars from the perspective of apoptosis to explore the etiology and pathogenesis of hypertensive disorders in pregnancy, to find new prevention and clinical treatment