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目的探讨单侧多中心性乳腺癌的临床特点及治疗方法。方法回顾性分析2004年7月—2007年12月14例单侧多中心性乳腺癌的临床资料。结果14例中浸润性小叶癌占42.9%(6/14),浸润性导管癌占57.1%(8/14)。多中心性癌灶数目为2～9枚,直径0.5～4.3 cm,12例癌灶分布在外上象限;1例分布于外上象限和内上象限;1例分布于外上象限,及外上象限与内上象限,外上象限与外下象限交界处。1例采用保乳根治术,随访3～5年无复发;13例采用乳腺癌改良根治术,随访2～37个月无复发。结论全组单侧多中心性乳腺癌病灶多分布在同一象限或相邻象限,以浸润性导管癌为主,治疗方法采用乳腺癌改良根治术为主的综合治疗。
Objective To investigate the clinical features and treatment of unilateral multicentric breast cancer. Methods The clinical data of 14 patients with unilateral multicentric breast cancer from July 2004 to December 2007 were analyzed retrospectively. Results Of the 14 cases, there were 42.9% (6/14) infiltrating lobular carcinomas and 57.1% (8/14) infiltrating ductal carcinomas. The number of multicentric foci ranged from 2 to 9, with a diameter of 0.5 to 4.3 cm. Twelve foci were located in the upper quadrant; one in the upper quadrant and the upper quadrant; one in the upper quadrant and outside Quadrant and upper quadrant, upper quadrant and lower quadrant at the junction. One case was treated with conservative radical mastectomy. No recurrence was observed in 3 to 5 years follow-up. Thirteen cases were treated with radical mastectomy of breast cancer, and no recurrence was observed in 2 to 37 months. Conclusion The whole group of unilateral multicentric breast lesions are mostly located in the same quadrant or adjacent quadrant with invasive ductal carcinoma as the main treatment. The treatment is based on the modified radical mastectomy of breast cancer.