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目的研究分析保乳手术与改良根治术在早期乳腺癌治疗中的疗效。方法将2013-2014年医院收治的早期乳腺癌患者120例按手术方式分为保乳治疗组和改良根治治疗组各60例。比较2组术中出血、手术时间及住院时间。结果保乳治疗组平均术中出血约(288.40±25.56)ml,平均手术时间(155.53±23.56)min,平均住院天数(12.50±1.50)d。改良根治治疗组术中出血约(423.60±29.56)ml,平均手术时间(195.53±26.30)min,平均住院天数为(18.50±1.50)d。2组比较差异有统计学意义(P<0.05)。保乳治疗组5年生存率为85.00%,改良根治组5年生存率为86.67%,2组比较差异无统计学意义(P>0.05)。结论保乳手术及改良根治术治疗早期乳腺癌均取得良好手术效果,但保乳手术具有术中出血少,术后恢复快,得临床进一步研究和推广。
Objective To study the effect of conservative surgery and modified radical mastectomy in the treatment of early breast cancer. Methods A total of 120 patients with early breast cancer admitted from 2013 to 2014 in our hospital were divided into two groups according to the operation method: breast conserving therapy group and modified radical therapy group. Two groups of intraoperative bleeding, operation time and hospitalization time were compared. Results The mean duration of intraoperative bleeding (288.40 ± 25.56) ml, mean operative time (155.53 ± 23.56) min and average length of hospital stay (12.50 ± 1.50) days in breast - conserving treatment group were significantly higher than those in control group. In the modified radical treatment group, the intraoperative bleeding was about (423.60 ± 29.56) ml, the average operation time was (195.53 ± 26.30) min, the average length of stay was (18.50 ± 1.50) d. The difference between the two groups was statistically significant (P <0.05). The 5-year survival rate of breast-conserving treatment group was 85.00%, and the 5-year survival rate of modified radical treatment group was 86.67%. There was no significant difference between the two groups (P> 0.05). CONCLUSION: Breast-conserving surgery and modified radical mastectomy have achieved satisfactory results in the treatment of early-stage breast cancer. However, breast-conserving surgery has less intraoperative bleeding and rapid recovery after operation, and is further studied and popularized in clinic.