论文部分内容阅读
目的了解患儿中枢神经系统腮腺炎病毒(Mumps virus,MV)的感染状况和其临床特征。方法收集2014年5月~2015年4月因病毒性脑炎在郴州市第一人民医院儿童医院住院患儿的血液样本130例,儿童保健门诊正常儿童的血液样本10例作为研究对照,应用间接酶联免疫方法检测MV Ig M抗体。结果 130例血液样本中,检出MV阳性10例(7.7%),男女各5例,MV阳性患儿的平均年龄46.11个月,其临床表现主要为发热、头痛、呕吐和抽搐,体征主要为颈抗阳性,平均住院时间17.7天,所有患儿全部治愈出院。MV阳性患儿的血液检查结果与对照组的血液检查结果,差异无统计学意义。结论 MV是本地区儿童病毒性脑炎不可忽视的病原,且腮腺炎病毒性脑炎的血液检查基本正常,不易诊断,故应提高儿童腮腺炎病毒性脑炎的诊断方法,并积极治疗,努力改善其预后。
Objective To investigate the infection status and clinical features of Mumps virus (MVD) in children. Methods From May 2014 to April 2015, 130 cases of children with viral encephalitis admitted to Children’s Hospital of Chenzhou First People’s Hospital and 10 cases of normal children’s blood samples from child health clinic were selected as research controls. ELISA was used to detect MV Ig M antibody. Results Among the 130 blood samples, 10 (7.7%) were positive for MV, 5 for both men and women, and the average age of MV-positive children was 46.11 months. The main clinical manifestations were fever, headache, vomiting and convulsions. The main signs were Cervical anti-positive, the average hospitalization time of 17.7 days, all children were cured and discharged. MV-positive children’s blood test results and the control group blood test results, the difference was not statistically significant. Conclusion MV is a pathogen of children with viral encephalitis in the region, and mumps virus encephalitis is basically normal blood tests, difficult to diagnose, it should be to improve the diagnosis of mumps viral encephalitis and positive treatment and efforts Improve their prognosis.