本文主要介绍作者课题组有关氧化三氟甲基化反应的提出背景及相关成果。从1995年到2008年的10余年间,我们从国内易得的含氟有机原料出发,发展了一系列含单氟(C-F)、二氟亚甲基(CF2)和三氟甲基(CF3)合成子的合成方法,并应用这些含氟合成子制备含氟氨基酸、含氟核苷和一些复杂天然产物的含氟类似物,通过测试发现一些具有生 This article mainly introduces the background and related achievements of the author’s research group on the oxidation of trifluoromethylation reaction. In the more than 10 years from 1995 to 2008, we developed a series of fluorinated organic materials containing monofluoro (CF), difluoro methylene (CF2) and trifluoromethyl (CF3) Synthetic methods, and the use of these fluorine-containing synthetic fluorine-containing amino acids, fluorine-containing nucleosides and some of the complex natural products of fluorine-containing analogues, found by some tests with students