论文部分内容阅读
目的 观察成人下颌下腺内瘦素和瘦素受体的表达和分布。方法 HE染色法和免疫组织化学SABC法。结果 成人下颌下腺内闰管、纹状管和部分小叶间导管上皮细胞呈瘦素及瘦素受体免疫阳性反应,免疫反应产物分布于导管上皮细胞胞质内,细胞核呈阴性反应。结论 成人下颌下腺内有瘦素和瘦素受体表达,可能参与调节胃肠功能及下颌下腺自身的分泌活动。
Objective To observe the expression and distribution of leptin and leptin receptors in adult submandibular glands. Methods HE staining and immunohistochemical SABC method. Results The leptin, leptin and some interlobular ductal epithelial cells in adult submandibular gland were immunopositive for leptin and leptin receptors. The immunoreaction products were distributed in the cytoplasm of the ductal epithelial cells with a negative reaction in the nucleus. Conclusion The expression of leptin and leptin receptors in adult submandibular glands may be involved in the regulation of gastrointestinal function and the secretory activity of the submandibular gland itself.