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通过对血清溶血素值、RES吞噬功能、IL 2的检测、NK细胞活性检测,研究亮菌多糖对小鼠免疫功能的影响.结果表明:亮菌多糖体内给药能激活小鼠网状内皮系统,增强其吞噬功能;能明显拮抗环磷酰胺所致的小鼠溶血素抗体的降低;能提高ConA诱导小鼠体内淋巴细胞产生白介素2的能力;可以增强小鼠脾脏NK细胞的活性.说明亮菌多糖能使小鼠机体免疫力增强.
The serum hemolysin value, RES phagocytosis, IL 2 detection, and NK cell activity assay were used to study the effect of P. lentiviens polysaccharides on immune function in mice. The results showed that P. elegans polysaccharides could activate mouse reticuloendothelial system in vivo. , enhance its phagocytosis; can significantly antagonize the reduction of mouse hemolysin antibody caused by cyclophosphamide; can increase the ability of ConA-induced lymphocyte production of interleukin 2 in mice; can enhance the activity of mouse spleen NK cells. Said bright Bacteria polysaccharide can enhance the body immunity of mice.