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目的探讨不同药物联合米非司酮终止瘢痕子宫中期妊娠的临床效果。方法将108例瘢痕子宫中期妊娠患者随机分为观察组与对照组各54例,观察组采用依沙吖啶联合米非司酮治疗,对照组采用米索前列醇联合米非司酮治疗,对2组患者产后出血量、宫缩时间、胎盘胎膜残留、总产程情况进行比较,观察2组孕妇流产成功率。结果观察组产后出血量、产后大出血及胎盘胎膜残留发生率均低于对照组,宫缩发动时间、总产程时间均短于对照组,流产成功率明显高于对照组,差异均有统计学意义(P<0.05)。结论在终止瘢痕子宫中期妊娠中采用依沙吖啶联合米非司酮治疗,能提高完全流产成功率,同时促进胎儿尽快娩出,效果显著。
Objective To investigate the clinical effects of different drugs in combination with mifepristone on the termination of uterine scar pregnancy. Methods A total of 108 patients with uterine scar pregnancy were randomly divided into observation group and control group, 54 cases in each group. The observation group was treated with ethacridine combined with mifepristone. The control group was treated with misoprostol combined with mifepristone. Postpartum hemorrhage, contractions time, residual fetal membranes and total labor were compared between the two groups to observe the success rate of abortion in two groups. Results The amount of postpartum hemorrhage, postpartum hemorrhage and placental residual rate in observation group were lower than those in control group. The time of uterine contractions and the length of labor were shorter than those in control group. The success rate of abortion was significantly higher than that of control group Significance (P <0.05). Conclusions Ethacridine combined with mifepristone can reduce the success rate of complete abortion and promote the delivery of the fetus as soon as possible in the termination of uterine scar pregnancy.