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目的探讨原田氏病的临床表现、药物治疗与荧光眼底血管造影特点。方法观察15例(28眼)原田氏病的临床表现并行眼底彩色照相和眼底荧光血管造影(fundusfluoresceinangiography,FFA)结果15例(28)眼原田氏病主要表现为视力下降、头痛、颈强、听力下降等症状。眼底为视乳头水肿、视网膜水肿,周边视网膜浆液性脱离或晚霞状眼底,相应的FFA检查结果为,急性期:眼底后极部及周边的“密集针尖状”荧光素渗漏;恢复期:眼底后极部弥散性色素上皮萎缩性高荧光,脉络膜大血管显露。甲基强的松龙冲击治疗后,15例(28眼)治疗后视力明显提高(P<0.05)。讨论FFA造影和糖皮质激素合理应用对原田氏病诊断及预后具有价值。
Objective To investigate the clinical manifestation, drug treatment and fluorescent fundus angiography of Hahn’s disease. Methods Fifteen patients (28 eyes) were treated with fundus fluorescein angiography (FFA) in 15 eyes (28 eyes). The results of fundus fluorescein angiography (FFA) showed 15 cases (28 eyes). Hahnoda’s disease manifested as vision loss, headache, neck ache, Decline and other symptoms. The fundus is papilledema, retinal edema, peripheral retinal serous detachment, or sunset-like fundus. The corresponding FFA results were acute phase: leakage of “dense needle-like” fluorescein at the posterior pole and periphery of the fundus; convalescence: fundus Posterior pole disseminated pigment epithelium atrophic high fluorescence, choroidal blood vessels revealed. After the treatment of methylprednisolone, the visual acuity of 15 cases (28 eyes) was significantly improved (P <0.05). Discussion FFA angiography and glucocorticoid rational use of the diagnosis and prognosis of Honda’s disease has value.