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目的探讨血清天冬氨酸氨基转移酶(AST)、γ-谷氨酰转肽酶(GGT)、丙氨酸氨基转移酶(ALT)、前白蛋白(PA)、血清白蛋白(ALB)、胆碱酯酶(CHE)、总胆汁酸(TBA)、总胆红素(TBIL)等指标检测结果诊断肝脏疾病的临床效果。方法 150例肝脏疾病患者为观察组,以同期接受体检的健康人员150例为对照组。两组均给予AST、GGT、ALT、PA、ALB、CHE、TBA、TBIL检测,并对比其检测结果。结果观察组AST(280.2±160.5)U/L、GGT(133.8±66.5)U/L、ALT(296.5±97.2)U/L、PA(166.2±55.6)mg/L、ALB(28.2±1.5)g/L、CHE(1660.2±600.5)U/L、TBA(75.7±45.5)μmol/L、TBIL(56.2±24.5)μmol/L;对照组AST(20.5±6.4)U/L、GGT(25.1±6.2)U/L、ALT(26.4±7.7)U/L、PA(326.5±60.8)mg/L、ALB(49.3±3.5)g/L、CHE(5468.7±925.5)U/L、TBA(8.4±3.5)μmol/L、TBIL(12.5±3.2)μmol/L。观察组AST、GGT、ALT、TBA、TBIL均明显高于对照组,而PA、ALB、CHE明显低于对照组,差异具有统计学意义(P<0.05)。观察组不同疾病患者AST、GGT、ALT、PA、ALB、CHE、TBA、TBIL检测结果比较差异有统计学意义(P<0.05)。结论 AST、GGT、ALT、PA、ALB、CHE、TBA、TBIL检测对鉴别肝脏疾病患者与健康人员有积极帮助,同时对鉴别患者肝脏疾病发展程度亦有重要意义,值得临床推广。
Objective To investigate the effects of serum aspartate aminotransferase (AST), γ-glutamyl transpeptidase (GGT), alanine aminotransferase (ALT), prealbumin (PA), serum albumin (ALB) Cholinesterase (CHE), total bile acid (TBA), total bilirubin (TBIL) and other indicators test results to diagnose the clinical effect of liver disease. Methods 150 cases of liver disease patients as observation group, taking the physical examination over the same period 150 cases of healthy control group. The levels of AST, GGT, ALT, PA, ALB, CHE, TBA and TBIL in both groups were compared, and the results were compared. Results The levels of AST in the observation group were 280.2 ± 160.5 U / L, 133.8 ± 66.5 U / L, 296.5 ± 97.2 U / L, 166.2 ± 55.6 mg / L and 28.2 ± 1.5 g / /L,CHE(1660.2 ±600.5)U/L,TBA(75.7 ± 45.5)μmol/L, TBIL(56.2 ± 24.5)μmol/L; control group, AST (20.5 ± 6.4) U / L, GGT (25.1 ± 6.2 ALT was 26.4 ± 7.7 U / L, PA was 326.5 ± 60.8 mg / L, ALB was 49.3 ± 3.5 g / L, CHE was 5468.7 ± 925.5 U / L, TBA was 8.4 ± 3.5 ) μmol / L, TBIL (12.5 ± 3.2) μmol / L. The levels of AST, GGT, ALT, TBA and TBIL in the observation group were significantly higher than those in the control group, while the levels of PA, ALB and CHE in the observation group were significantly lower than those in the control group (P <0.05). The differences of AST, GGT, ALT, PA, ALB, CHE, TBA and TBIL in different diseases in the observation group were statistically significant (P <0.05). Conclusion The detection of AST, GGT, ALT, PA, ALB, CHE, TBA and TBIL are helpful to identify patients with liver diseases and healthy people. It is also of great significance in identifying the degree of development of liver disease in patients and is worthy of clinical promotion.