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近年来由于应用了染色体分带技术,对多数甚至全部急性非淋巴细胞白血病(ANLL)病人的异常克隆染色体有可能进行鉴定。已发现异常克隆染色体同ANLL的特殊亚型及预后有关,如M2型存在t(8;21),M3型及其变异亚型存在t(15;17)。本文报导ANLL中一种新的细胞遗传学一一临床病理联合即第16对染色体中一条长臂部份缺失和骨髓嗜酸细胞增多。作者对1980年1月-1982年4月间住在明尼苏达医
In recent years, due to the application of chromosome zoning technology, most or even all of the acute non-lymphocytic leukemia (ANLL) abnormal cloned chromosomes may be identified. Abnormal clonal chromosomes have been found to be associated with specific subtypes and prognoses of ANLL, such as t (8; 21) for M2 and t (15; 17) for M3 and its variant subtypes. This article reports a new cytogenetics-ANLL clinical and pathological joint that is a chromosome 16 in the absence of a long arm and bone marrow eosinophilia. The author lived in Minnesota between January 1980 and April 1982