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目的探讨替米沙坦联用卡维地络对左室舒张功能不全的治疗价值。方法34例左室舒张功能不全患者作为观察组给予替米沙坦与卡维地络口服;38例作为对照组口服钙拮抗剂,分别于治疗前治疗后6个月记录舒张早期峰值血流速度(EV)、舒张晚期峰值血流速度(AV)、E/A、E峰减速时间(EDT)、等容舒张时间(IRT)。结果观察组的左室舒张功能较对照组改善明显(P<0.05~0.01)。结论替米沙坦与卡维地络联用能有效改善患者左室舒张功能。
Objective To investigate the therapeutic value of telmisartan combined with carvedilol on left ventricular diastolic dysfunction. Methods Twenty-four patients with left ventricular diastolic dysfunction were given telmisartan and carvedilol orally as control group. Thirty-eight patients as control group were given oral calcium antagonist, and the peak diastolic velocity was recorded at 6 months after pretreatment (EV), peak late diastolic velocity (AV), E / A, E peak decelerating time (EDT) and isovolumic relaxation time (IRT). Results The left ventricular diastolic function of the observation group improved significantly compared with the control group (P <0.05 ~ 0.01). Conclusion Telmisartan combined with carvedilol can effectively improve left ventricular diastolic function in patients.