论文部分内容阅读
白天PaO_2>55mmHg的慢性阻塞性肺病(COPD)患者在快速眼动(REM)睡眠与非REM睡眠时氧下降不具预测性,睡眠呼吸暂停综合征周期性减饱和是疾病诊断的基础,多导睡眠图(PSG)测定夜间低氧血症昂贵、费力,需研究排除无重要睡眠呼吸疾病的方法。1987年文献报道整夜尿的尿酸廓清率(△UA:Cr)能很好地作为严重低氧血症的标记,ATP降解为尿酸在低氧的动物模型增加,AMP的分解代谢在血氧正常时成为尿囊素,低氧时为尿酸,人和动物尿酸产物能作为
Patients with chronic obstructive pulmonary disease (COPD) with PaO 2> 55 mm Hg during daytime have unpredictable oxygen drops during REM and non-REM sleep. Periodic hyponatremia in sleep apnea syndrome is the basis of disease diagnosis. Polysomnography Figure (PSG) Determination of nocturnal hypoxemia expensive, laborious, need to study the exclusion of non-critical sleep-disordered breathing method. In 1987, it was reported in the literature that overnight urine uric acid clearance (ΔUA: Cr) was a good marker of severe hypoxemia. ATP was degraded to uric acid in an animal model of hypoxia. AMP catabolism was normal When allantoin, uric acid hypoxia, human and animal uric acid products can be as