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目的 研究HSP70在星形细胞瘤中的表达与肿瘤病理分级的关系,探讨HSP70在星形细胞瘤预后判断上的价值。方法 用SP免疫组化方法对96例星形细胞瘤中HSP70的表达进行研究。结果 在星形细胞瘤中,HSP70的阳性表达随星形细胞瘤的病理分级增高而增加。结论 结合脑星形细胞瘤的病理组织分级,HSP70的表达能反映星形细胞瘤的恶性进展,从而对判断的预后有一定价值。
Objective To study the relationship between the expression of HSP70 and the histopathological grade in astrocytoma and to explore the value of HSP70 in the prognosis of astrocytoma. Methods SP immunohistochemistry was used to study the expression of HSP70 in 96 cases of astrocytoma. Results In astrocytoma, the positive expression of HSP70 increased with the pathological grade of astrocytoma. Conclusion Combined with the pathological grade of astrocytoma, the expression of HSP70 can reflect the malignant progression of astrocytomas, and thus has some value in judging the prognosis.