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目的 :探讨T淋巴细胞亚群检测在腹水鉴别诊断中的价值。方法 :对 92例腹水患者 ,其中结核性腹膜炎腹水 38例 ,肝硬化腹水 2 9例 ,癌性腹水 2 5例 ,用流式细胞仪测定其腹水T淋巴细胞亚群。结果 :腹水中T淋巴细胞 (CD 3+ )、T辅助 /诱导细胞亚群 (CD4+ )、T辅助细胞亚群 /T抑制细胞亚群 (CD 4+ /CD 8+ )由高到低依次为结核性腹膜炎腹水 >癌性腹水 >肝硬化腹水 (P <0 .0 1 ) ;CD 8+ 由高到低依次为癌性腹水 >结核性腹膜炎腹水 >肝硬化腹水 (P <0 .0 1 )。结论 :T淋巴细胞亚群在结核性腹膜炎、肝硬化及癌性腹水中存在明显差异。腹水T淋巴细胞亚群检测可用于腹水的鉴别诊断。
Objective: To investigate the value of T lymphocyte subsets in the differential diagnosis of ascites. Methods: Ninety-two patients with ascites were enrolled, including 38 cases of tuberculous peritonitis, 29 cases of cirrhosis and 25 cases of cancerous ascites. The T-lymphocyte subsets of ascites were determined by flow cytometry. RESULTS: The levels of T lymphocytes (CD 3+), T helper / induced cell subsets (CD4 +) and T helper subsets / T suppressor cell subsets (CD 4+ / CD 8+) in ascites were Tuberculous peritonitis ascites> cancerous ascites> liver cirrhosis ascites (P <0.01); CD 8+ descending order of cancerous ascites> tuberculous peritonitis ascites> cirrhosis ascites (P <0.01) . Conclusion: T lymphocyte subsets in tuberculous peritonitis, cirrhosis and cancerous ascites there are significant differences. Ascites T lymphocyte subsets detection can be used for the differential diagnosis of ascites.