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目的 :探讨子宫颈癌术前行子宫动脉栓塞化疗的方法及疗效。方法 :对 2 1例子宫颈癌 (Ⅰb期 4例 ,Ⅱa期 7例 ,Ⅱb期10例 )行超选择性子宫动脉栓塞化疗 ,观察其疗效和毒副反应。介入性化疗后 2周行子宫根治术及盆腔淋巴结清扫术。结果 :2 1例患者症状均明显缓解 ,近期有效率达 95 .2 % ,手术成功率达 10 0 %。 2 0例各组淋巴结及切缘无癌 ,1例左髂内淋巴结转移 ,补充放疗。 1例子宫颈小细胞癌术后全身化疗 3个疗程。随访 2 1例均健在 ,生存时间 1～ 18个月。结论 :子宫颈癌术前超选择性子宫动脉栓塞化疗 ,有助于提高手术治愈率 ,减少复发和转移
Objective: To investigate the method and efficacy of uterine artery embolization chemotherapy before cervical cancer. Methods: Twenty-one cases of cervical cancer (4 cases of stage Ib, 7 cases of stage IIa and 10 cases of stage IIb) underwent superselective uterine artery embolization and chemotherapy. The curative effect and toxicity were observed. Two weeks after interventional chemotherapy, radical hysterectomy and pelvic lymph node dissection were performed. Results: The symptoms of 21 patients were significantly relieved. The effective rate was 95.2% and the successful rate was 100%. Twenty cases in each group had no lymph nodes and no tumor margins, and one patient had left internal iliac lymph node metastasis and received radiotherapy. 1 case of small cell carcinoma of the cervix after 3 cycles of systemic chemotherapy. All 21 cases were followed up for a median of 1 to 18 months. Conclusion: Preoperative ultra-selective uterine artery embolization chemotherapy for cervical cancer can help to improve the cure rate and reduce recurrence and metastasis