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[目的]探讨仰卧位与俯卧位等体位下实施三维适形(3D-CRT)与调强放射治疗(IMRT)计划对直肠癌患者小肠受照体积的影响。[方法]选择50例直肠癌患者,让其膀胱处于充盈条件下,在仰卧位与俯卧位分别进行CT定位扫描,将扫描图像传输到计划系统。在每一种体位上所得到的CT图像上分别实施3D-CRT与IMRT计划,观察患者在不同技术及体位下小肠受照体积(V5-45)的差异。[结果]在相同的体位(仰卧位或俯卧位)下,与3D-CRT比较,IMRT治疗下小肠V_(45)显著下降(P<0.05),小肠V_(15)则两者较为接近。在相同的放疗技术(3D-CRT或IMRT)下,与仰卧位比较,俯卧位治疗小肠V_(45)与V_(15)均显著下降(P<0.05)。[结论]直肠癌患者在接受体外照射治疗时,治疗体位较放疗技术对患者小肠受照体积的影响更显著。
[Objective] To investigate the effect of three-dimensional conformal (3D-CRT) and intensity-modulated radiation therapy (IMRT) programs on the volume of small intestine in patients with rectal cancer under supine and prone position. [Method] Fifty patients with rectal cancer were selected, their bladder was filled, CT scanning was performed respectively in supine and prone position, and the scanned images were transmitted to the planning system. The 3D-CRT and IMRT plans were performed on CT images obtained from each position to observe the differences in the volume of small intestine (V5-45) among patients under different techniques and positions. [Result] Compared with 3D-CRT, the V_ (45) in intestinal of IMRT significantly decreased (P <0.05) and V_ (15) of small intestine in the same position (supine position or prone position). Under the same radiotherapy technique (3D-CRT or IMRT), the V_ (45) and V_ (15) in the prone position decreased significantly compared with the supine position (P <0.05). [Conclusion] Rectal cancer patients receiving radiation therapy in vitro, the treatment of position than radiotherapy technology in patients with small intestine volume affected more significantly.