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目的:探讨棕树籽对雄性大鼠生育力的影响。方法:将40只雄性SD大鼠随机分为空白组,棕树籽煎剂高、中、低剂量组,每组10只,棕树籽煎剂高、中、低剂量组每次给药20 mL.kg-1(生药量分别为60g.kg-1、40g.kg-1、20g.kg-1),空白组给予生理盐水,每天1次,连续灌胃14天,观察雄鼠的不育期、体外活性精子数及雌鼠受孕率。结果:与空白组比较,棕树籽煎剂高、中剂量组受孕率降低、不育期延长,高剂量组活性精子数降低,差异有统计学意义(P<0.05,P<0.01)。结论:棕树籽有一定的降低雄性大鼠生育力的作用。
Objective: To investigate the effects of palm tree seed on the fertility of male rats. Methods: Forty male Sprague-Dawley rats were randomly divided into blank group, high, medium and low dose of palm tree seed decoction, 10 rats in each group. The rats in high, medium and low dose groups were given 20 mL.kg-1 (crude drug doses were 60g.kg-1, 40g.kg-1, 20g.kg-1), the blank group were given normal saline once a day for 14 days, Education period, the number of sperm in vitro activity and female pregnancy rate. Results: Compared with the blank group, the decoction of palm tree seed decoction reduced the pregnancy rate, prolonged the period of infertility and the number of active sperm in the high dose group, the difference was statistically significant (P <0.05, P <0.01). Conclusion: Palm seed has the effect of reducing the fertility of male rats.