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目的:探讨药学指导对糖尿病患者用药依从性的影响。方法:将我院收治的糖尿病患者104例随机分为对照组和研究组,各52例。对照组给予常规降糖药物治疗,研究组在常规降糖药物治疗基础上给予药学指导,比较两组血糖变化及治疗期用药依从性。结果:研究组用药依从性良好率96.15%高于对照组的67.31%,差异有统计学意义(P<0.05);两组治疗前FBG、2h PBG、HbAlc血糖指标水平差异不具有统计学意义(P>0.05),治疗后,两组血糖指标水平均明显降低(P<0.05),且研究组血糖指标均低于对照组(P<0.05)。结论:药学指导对糖尿病患者用药依从性的影响效果显著,可提高用药依从性,且降糖效果好,可用于指导临床合理用药。
Objective: To investigate the influence of pharmacy guidance on drug compliance in diabetic patients. Methods: 104 cases of diabetic patients admitted to our hospital were randomly divided into control group and study group, with 52 cases each. The control group was given conventional hypoglycemic drugs. The research group was given the pharmacological guidance on the basis of conventional hypoglycemic drugs treatment. The blood glucose changes and the medication adherence during the treatment period were compared. Results: The good rate of drug compliance in study group was 96.15%, which was significantly higher than 67.31% in control group (P <0.05). There was no significant difference in the level of blood glucose between FBG, 2h PBG and HbAlc (P <0.05). After treatment, the levels of blood glucose in both groups were significantly decreased (P <0.05), and the levels of blood glucose in the study group were lower than those in the control group (P <0.05). Conclusion: Pharmacological guidance has significant effect on drug compliance in patients with diabetes, which can improve drug compliance, and hypoglycemic effect, and can be used to guide clinical rational drug use.