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胫前黏液性水肿属于Graves甲状腺机能亢进症(甲亢)较为少见的临床表现之一,是由于局部自身免疫异常引起的皮肤增厚、变形或结节形成,病变通常不典型,但严重患者可以发展为象皮肿和杵状指,绝大部分患者可伴有甲状腺相关眼病。其诊断需结合病史及皮肤病变,治疗除控制原发病以外,还包括局部注射或外涂糖皮质激素、全身免疫调节治疗、物理治疗等。本文就甲亢合并胫前黏液性水肿的诊治进展作一综述。
Anterior tibial myxedema is one of the less common clinical manifestations of hyperthyroidism (hyperthyroidism) in Graves due to thickening, degeneration or nodule formation of the skin due to local autoimmune abnormalities, which are usually atypical but may develop in severe cases For the edema and clubbing, the vast majority of patients may be associated with thyroid-related eye disease. The diagnosis should be combined with medical history and skin lesions, the treatment of primary disease in addition to control, including local injection or external glucocorticoid, systemic immunomodulatory therapy, physical therapy and so on. This article reviews the diagnosis and treatment of hyperthyroidism complicated with anterior tibial edema.