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目的分析乙型肝炎(乙肝)血清标志物检出率的变化情况。方法对2000例患者的乙型肝炎血清标志物筛查结果 ,采用AxSYM微粒子酶免疫分析技术对其进行乙型肝炎血清标志物检测,对各项标志物及其检出率进行回顾性分析。结果乙型肝炎血清标志物中的乙肝表面抗原(HBsAg)、乙肝E抗原(HBeAg)、乙肝表面抗体(抗-HBs)、乙肝e抗体(抗-HBe)、乙肝核心抗体(抗-HBc)检出率各有不同,从高到低排列分别为抗-HBc(55.1%)、抗-HBs(47.9%)、抗-HBe(28.4%)、HBsAg(9.3%)、HBeAg(2.6%);同时,男性各乙肝血清标志物检出率要高于女性,差异有统计学意义(P<0.05)。结论乙型肝炎病毒感染率仍然比较高,而乙型肝炎血清标志物的检出率呈缓慢下降的趋势,临床需引起重视。
Objective To analyze the change of the detection rate of hepatitis B (hepatitis B) serum markers. Methods Serological markers of hepatitis B were detected in 2000 patients with hepatitis B serum markers by AxSYM microparticle enzyme immunoassay. Retrospective analysis of the markers and their detection rate were performed. Results HBsAg, HBeAg, HBsAg, HBeAg and HBcAg in hepatitis B serum markers The rates varied from high to low with anti-HBc (55.1%), anti-HBs (47.9%), anti-HBe (28.4%), HBsAg (9.3%) and HBeAg , Male hepatitis B serum markers higher than the detection rate of women, the difference was statistically significant (P <0.05). Conclusion Hepatitis B virus infection rate is still relatively high, while the detection rate of hepatitis B serum markers showed a slow decline in clinical need to pay attention.