我院１９８６年７月至１９９２年１２月对４０例重型血友病甲施行了５９次同种脾细胞输注，结果除２例血浆Ⅷ因子水平不升外，其余输注后２～７天Ⅷ因子水平均明显升高，平均升高５～２０．１％，最高１例达６１．７％，Ⅷ因于水平一般于输后４～８周逐渐下降。４０例受者中有９例反复输注脾细胞２～３次，每次间隔半个月至５个月不等，重复输注后可使Ⅷ因子再度上升，此法简便、安全、反复输注可弥补远期疗效不佳的缺点。 In our hospital from July 1986 to December 1992 40 cases of severe hemophilia A administered 59 times the same splenocyte infusion, the results in addition to two cases of plasma factor VIII levels did not rise, the remaining 2 to 7 days after infusion Ⅷ factor levels were significantly increased, with an average increase of 5 ~ 20.1%, the highest in 1 case up to 61.7%, Ⅷ level as a general decline in 4 to 8 weeks after the fall. Among 40 recipients, 9 cases repeated infusion of splenocytes 2 to 3 times, each interval of half a month to 5 months, repeat infusion can make Ⅷ factors rise again, this method is simple, safe, repeated lose Note can make up for the shortcomings of poor long-term efficacy.