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目的 研究大鼠胆汁中 β 榄香烯的代谢产物。 方法 采用质谱、核磁共振、红外、紫外分析法对ivβ 榄香烯后大鼠胆汁样品进行分析。结果 确定了一个代谢产物的结构为 1 甲基 1 乙烯基 2 异丙烯基 4 异丙烯醛基环己烷。结论 β 榄香烯在体内存在生物转化过程。
Objective To study the metabolites of β-elemene in rat bile. Methods The bile samples of ivβ-elemene rats were analyzed by mass spectrometry, nuclear magnetic resonance, infrared and ultraviolet spectroscopy. As a result, the structure of one metabolite was confirmed to be 1-methyl-1-vinyl-2-isopropenyl-4-isopropenylcyclohexane. Conclusion β elemene exists in vivo biotransformation process.