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用双脉冲白质电刺激研究了87个大鼠视皮层神经元的短时程时间整合特性。第一个脉冲所引起的细胞反应对第二个反应有影响的细胞占被记录细胞总数的55.2%,其中表现为突触作用增强的占41.7%,表现为突触作用压抑的占58.3%。整合作用的强度决定于两个脉冲之间的时间间隔,作用形式主要表现为第二个刺激所引起的反应的幅度和时程的改变。电反应可以EPSP或IPSP为主,或由EPSP和IPSP混合组成。部分细胞的反应包含快慢两个成份,时间整合作用对不同反应成份的影响程度有明显的不同。在锥体神经元中,增强型和压抑型的比例大致相等,而非锥体神经元只显示压抑型作用。位于皮层深层的神经元有时间整合作用的比率(37.5%)比位于浅层的神经元(60.5%)要低得多。
Two-pulse white matter stimulation was used to investigate the short-term temporal integration of 87 rat visual cortical neurons. The first pulse of the cell response caused by the second reaction affected cells accounted for 55.2% of the total number of cells recorded, which showed an increase of synaptic effects accounted for 41.7%, the performance of the synaptic depression Accounting for 58.3%. Intensity of the integration depends on the time interval between the two pulses, the role of the main forms of the second stimulus caused by the reaction amplitude and duration changes. The electrical reaction can be predominately EPSP or IPSP or consist of a mixture of EPSP and IPSP. Part of the cellular response contains two components fast and slow, the time of the integration of different components of the impact of significant differences. In pyramidal neurons, the proportion of enhanced and depressed types is approximately equal, whereas non-pyramidal neurons show only repressive effects. Neurons in the deep cortex had a much lower rate of temporal integration (37.5%) than neurons in the shallow layer (60.5%).