本文使用免疫酶标技术ＡＢＣ法研究了ＨＬ６０，ＭＧＣ８０和ＭＣＦ７三个细胞系中ＭＣＳＦ及其受体的表达，结果表明，在ＨＬ６０和ＭＣＦ７细胞系中，ＭＣＳＦ和ＭＣＳＦ受体在细胞膜、细胞质和细胞核中均有表达，而ＭＧＣ８０细胞系的ＭＣＳＦ和ＭＣＳＦ受体只在细胞膜和细胞质中出现阳性表达，而细胞核未见阳性表达。ＭＣＳＦ和ＭＣＳＦ受体在上述细胞系中，其表达可能暗示上述细胞系存在自分泌现象。此外，本文还讨论了ＭＣＳＦ及其受体的核内分布的可能机制及其意义。 In this study, the expression of MCSF and its receptors in three cell lines HL60, MGC80 and MCF7 was studied using immunohistochemical technique—ABC method. The results showed that in the HL60 and MCF7 cell lines The MCSF and MCSF receptors are expressed in the cell membrane, cytoplasm, and nucleus, whereas the MCSF and MCSF receptors in the MGC80 cell line are only positively expressed in the cell membrane and cytoplasm, while the nucleus No positive expression was observed. The expression of M-CSF and M-CSF receptors in the above cell lines may suggest that the above cell lines have an autocrine phenomenon. In addition, this paper also discusses the possible mechanism and significance of intranuclear distribution of MCSF and its receptors.