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目的:分析社区老年人药物不良事件(ADE)发生原因,寻求防范对策,促进社区老年患者的安全合理用药。方法:收集本区2007-2008年40个社区卫生服务站ADE病例118份,按照涉及的药品种类及品种、给药途径、原因分类、不良事件临床表现等进行统计分析。结果:118例ADE中抗感染药物居首位,其次为中药注射剂;涉及系统以皮肤及其附件表现最为常见;相关原因包括选择药物不当,合用药物过多,用量、操作、储存等不当。结论:ADE的发生与多种因素有关,通过加强对社区卫生服务中的医、药、护等人员的培训和管理,慎重选择新药、特药,并加强对社区老年人合理用药知识的健康宣教,合理膳食等,是减少社区老年人ADE发生的关键。
Objective: To analyze the causes of adverse drug events (ADEs) in community elders and to seek preventive measures to promote safe and rational drug use in elderly patients in the community. Methods: A total of 118 ADE cases from 40 community health service stations in the district from 2007 to 2008 were collected and statistically analyzed according to the types and varieties of drugs involved, the route of administration, the cause classification, and the clinical manifestations of adverse events. Results: Among the 118 ADEs, anti-infectives ranked the top, followed by traditional Chinese medicine injections. The most common manifestation was the skin and its appendages. Other related reasons included inappropriate drug selection, overdose of drugs, improper dosage, handling and storage. Conclusion: The occurrence of ADE is related to many factors. By strengthening the training and management of medicine, medicine, nursing and other personnel in community health service, the careful selection of new drugs and special drugs and the health education of rational use of drugs in the community are strengthened , Reasonable diet, etc., is to reduce the incidence of ADE in the community the key.