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目的分析口腔颌面部间隙感染的临床特征,并探讨高压氧联合脓肿切开引流术的治疗效果。方法选择2009年1月-2013年12月收治的240例口腔颌面部感染患者,将其随机分为研究组123例和对照组117例;收集并分析患者的临床资料,了解其感染部位、感染源,再进行细菌培养,分析病原菌的种类;对照组给予常规治疗,研究组在对照组基础上行脓肿切开引流术联合高压氧治疗,对比两组患者的临床疗效及并发症发生率,所有数据均采用SPSS 17.0统计软件进行分析。结果患者感染部位主要以颌下间隙感染率最高,为37.91%,其次眶下间隙为23.33%;感染源以牙源性感染率最高,为59.17%,其次腺源性感染为26.25%;共培养出186株病原菌,其中革兰阳性菌79株占42.47%,革兰阴性菌107株占57.53%;治疗后研究组总有效率为91.87%、对照组为82.05%,研究组治疗效果显著高于对照组,差异有统计学意义(χ2=4.252,P<0.05)。结论高压氧联合脓肿切开引流术能够有效提高口腔颌面部间隙感染的临床疗效,降低并发症发生的风险,值得临床借鉴。
Objective To analyze the clinical characteristics of oral maxillofacial space infection and to explore the therapeutic effect of hyperbaric oxygen combined with abscess incision and drainage. Methods From January 2009 to December 2013, 240 patients with oral and maxillofacial infection were selected and randomly divided into study group (123 cases) and control group (117 cases). The clinical data of the patients were collected and analyzed to find out the location of the infection, Infection, and then bacterial culture, analysis of the types of pathogens; control group given routine treatment, the study group in the control group abscess incision and drainage combined with hyperbaric oxygen treatment, the two groups of patients compared the clinical efficacy and incidence of complications, all Data were analyzed using SPSS 17.0 statistical software. Results The highest infection rate was 37.91% in submandibular space and 23.33% in suborbital space. The highest rate of odontogenic infection was 59.17% and the second was gonococcal infection was 26.25% Out of 186 pathogens, 79 strains of Gram-positive bacteria accounted for 42.47% and 107 strains of Gram-negative bacteria accounted for 57.53%. After treatment, the total effective rate was 91.87% in the study group and 82.05% in the control group. The treatment effect in the study group was significantly higher than that in the study group Control group, the difference was statistically significant (χ2 = 4.252, P <0.05). CONCLUSION: Hypertension combined with abscess incision and drainage can effectively improve the clinical efficacy of oral and maxillofacial space infection and reduce the risk of complications, which is worthy of clinical reference.