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目的探讨同型半胱氨酸与急性心肌梗死的相关性。方法选取我院2013年2月至2014年2月急性心肌梗死患者50例设为观察组,对照组50例患者取医院体检健康成人。观察两组血脂(总胆固醇、三酰甘油、低密度胆固醇脂蛋白、高密度胆固醇脂蛋白)水平及同型半胱氨酸水平。结果经过测定发现,观察组患者总胆固醇、三酰甘油、低密度胆固醇脂蛋白、高密度胆固醇脂蛋白较对照组有明显上升,差异均有统计学意义(均P<0.05)。观察组患者同型半胱氨酸为(25±10),对照组健康成人同型半胱氨酸水平为(6.4±1.6)。两组样本同型半胱氨酸水平差异有统计学意义(P<0.05)。结论与健康成人相比,急性心肌梗死患者同型半胱氨酸水平与血脂水平明显上升,表明同型半胱氨酸水平与急性心肌梗死呈正相关性,在临床诊断中可将同型半胱氨酸水平作为急性心肌梗死诊断的标准之一。
Objective To investigate the correlation between homocysteine and acute myocardial infarction. Methods Fifty patients with acute myocardial infarction in our hospital from February 2013 to February 2014 were selected as the observation group and 50 patients in the control group were admitted to hospital for health examination. The levels of blood lipids (total cholesterol, triglyceride, low density cholesterol lipoprotein, high density cholesterol lipoprotein) and homocysteine in the two groups were observed. Results The results showed that total cholesterol, triglyceride, low density cholesterol lipoprotein and high density cholesterol lipoprotein in the observation group were significantly higher than those in the control group (all P <0.05). The homocysteine level in the observation group was (25 ± 10) and that in the control group was (6.4 ± 1.6). There was significant difference between two groups of homocysteine levels (P <0.05). Conclusion Compared with healthy adults, patients with acute myocardial infarction, homocysteine levels and lipid levels increased significantly, indicating that homocysteine levels and acute myocardial infarction was positively correlated to the clinical diagnosis of homocysteine levels As one of the criteria for the diagnosis of acute myocardial infarction.