论文部分内容阅读
目的:比较连续性肾脏替代治疗与间歇性血液透析对急性肾损伤的临床疗效。方法:回顾性分析从2014年2月到2016年2月来我院治疗的急性肾损伤患者50例,按照治疗方法分为连续性肾脏替代治疗(Continuous renal replacement therapy,CRRT)组与间歇性血液透析(Intermittent hemodialysis,IHD)组,每组各25例。记录两组治疗前的基线数据,治疗前与治疗后的血清C-反应蛋白(C-reactive protein,CRP)、血肌酐(Serum creatinine,SCr)含量以及尿量恢复时间、重症监护室(Intensive care unit,ICU)住院时间、心血管事件发生率。结果:CRRT组与IHD组治疗前的一般资料以及尿量、血清CRP、SCr水平比较差异均无统计学意义(P>0.05)。治疗1周后,与IHD组相比,CRRT组血清CRP、SCr水平明显下降,尿量恢复时间、ICU住院时间均明显缩短,心血管发生率(32.0%vs.64.0%)明显下降,差异均具有统计学意义(P<0.05)。结论:CRRT治疗急性肾损伤能有效改善患者肾功能,缩短ICU住院时间并提高治疗安全性。
Objective: To compare the clinical effects of continuous renal replacement therapy and intermittent hemodialysis on acute renal injury. Methods: A retrospective analysis of 50 patients with acute kidney injury who came to our hospital from February 2014 to February 2016 was divided into two groups: continuous renal replacement therapy (CRRT) group and intermittent blood Intermittent hemodialysis (IHD) group, 25 cases in each group. The baseline data before treatment, the levels of C-reactive protein (CRP), serum creatinine (SCr) and urine output before and after treatment were recorded. Intensive care Unit, ICU) Length of stay, cardiovascular event rate. Results: There was no significant difference in general data, urine volume, serum CRP and SCr levels between CRRT group and IHD group before treatment (P> 0.05). After 1 week of treatment, compared with IHD group, serum CRP and SCr levels in CRRT group decreased significantly, urine output time and hospital stay in ICU significantly shortened, and cardiovascular incidence (32.0% vs.64.0%) decreased significantly Statistically significant (P <0.05). Conclusion: CRRT treatment of acute renal injury can effectively improve renal function, shorten ICU hospital stay and improve the safety of treatment.