根据临床需要,我们研制了烧伤喷膜气雾剂,用于治疗烧烫伤,使用方便,临床效果满意,现报道如下。 1 处方 虎仗900g,紫草茸200g,黄芩300g,白及100g,地榆200g,冰片60g,2％苯氧乙醇50g,盐酸达克隆2g。 2 制法 将虎仗、黄芩、白及、地榆粗粉,照中国药典1995年版一部附录酊剂项下的浸渍法,用50％的乙醇1000ml浸泡两周,使有效成分充分浸出,倾取上层液,用布滤过,残渣用力压榨,使残液尽可能压出,与滤液合并,静止24h,滤过,向滤液中加入盐酸达克隆备用。冰片和紫草茸用适量乙醇溶解,加入苯氧乙醇搅匀后,再与备用液合并,补加乙醇使含醇量达到75％,振摇均匀。然后,取100g混合液,装入特制的铁筒中,再加50g氯乙烷,加上阀门紧密封闭后,在12kg/cm~2的压力下,向铁筒灌入抛射剂——氟里昂(F_(12)50g,即得。 把装好抛射剂的瓶放在42℃温水中做漏气试验,保证封口紧密,合格者即为成品。 According to clinical needs, we have developed a burn spray film aerosol, used for the treatment of burns and burns, easy to use, satisfactory clinical results, are reported below. 1 prescription tiger squid 900g, comfrey 200g, astragalus 300g, white and 100g, medlar 200g, borneol 60g, 2% phenoxyethanol 50g, hydrochloric acid clone 2g. 2 Preparation of tiger cockroach, yellow cockroach, white cockroach and earthworm coarse powder, according to the impregnation method in the Chinese Pharmacopoeia 1995 edition of an appendix topping agent, soaking for 5 weeks with 1000 ml of 50% ethanol to fully leaching the active ingredient The upper liquid was filtered through a cloth, the residue was pressed hard, the residue was pressed out as much as possible, and the filtrate was combined and was left to stand still for 24 hours, filtered, and hydrochloric acid was added to the filtrate for cloning. The borneol and comfrey were dissolved in an appropriate amount of ethanol, mixed with phenoxyethanol, and then combined with the stock solution. The amount of alcohol was increased by 75% with shaking and even shaking. Then, take 100g of the mixture, and put it into a special iron cylinder, add 50g of ethyl chloride. After the valve is closed tightly, pour the propellant, Freon, into the iron cylinder under a pressure of 12kg/cm 2 . F_(12)50g, that is to say. Put the bottle with the propellant on the hot water at 42°C to make a gas leakage test to ensure that the seal is tight and the qualified person is the finished product.