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目的分析温州市瓯海区社区居民脂肪肝的流行现状及其影响因素。方法采用整群抽样的方法抽取2个社区1 872名≥18岁的常住居民进行问卷调查、普通体检、超声波检查和实验室检测。用SPSS 13.0软件进行数据统计分析,计数资料用率来表示,组间比较用χ2检验;计量资料用均数±标准差(x±s)表示,组间比较用独立样本t检验;危险因素分析用非条件logistic回归分析,选用Forward LR逐步法,进入标准为0.05,剔除标准为0.10;P<0.05为差异有统计学意义。结果温州市瓯海区社区居民脂肪肝标化患病率为11.96%,其中男性为14.58%,女性为10.26%。脂肪肝患病率随年龄的增加总体呈上升趋势,脂肪肝组的体质指数(BMI)、腰围、收缩压(SBP)、舒张压(DBP)、血糖(FPG)、甘油三酯(TG)、血清胆固醇(TC)和低密度脂蛋白胆固醇(LDL-C)检测均值高于正常组,高密度脂蛋白胆固醇(HDL-C)检测均值低于正常组,差异均有统计学意义(P<0.05)。Logistic多因素逐步回归分析结果显示,腰围粗、体质指数大、高TC血症、高TG血症、低HDL-C血症、糖尿病、超重和肥胖以及中心性肥胖是脂肪肝患病的危险因素。结论瓯海区社区居民脂肪肝的患病率较高,肥胖、高脂血症及其相关的代谢紊乱与脂肪肝的患病关系密切。
Objective To analyze the prevalence and influencing factors of fatty liver in community residents in Ouhai District of Wenzhou City. Methods A total of 1 872 permanent residents aged 18 years or older in 2 communities were sampled by cluster sampling method for questionnaire survey, general physical examination, ultrasonic examination and laboratory test. SPSS 13.0 software for statistical analysis of data, the use of counting data to indicate that the comparison between groups using χ2 test; measurement data using mean ± standard deviation (x ± s) said the comparison between groups using independent samples t test; risk factor analysis Using unconditional logistic regression analysis, Forward LR stepwise method was used, with a standard of 0.05 and a standard of 0.10. P <0.05 was considered as statistically significant. Results The prevalence of fatty liver in community residents was 11.96% in Ouhai District of Wenzhou City, of which 14.58% for males and 10.26% for females. The prevalence of fatty liver increased with the increase of age. The body mass index (BMI), waist circumference, SBP, DBP, FPG, TG, The mean of serum cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) was higher than that of the normal group, while the mean of HDL-C was lower than that of the normal group (P <0.05 ). Logistic multivariate stepwise regression analysis showed that the patients with fatty liver were the risk factors of fatty liver, such as thick waistline, large body mass index, hypercholesteremia, hypercholesterolemia, hypo HDL-C, diabetes, overweight and obesity, and central obesity . Conclusion The prevalence of fatty liver in community residents in Ouhai district is high. The obesity, hyperlipidemia and related metabolic disorders are closely related to the prevalence of fatty liver.