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(1)本文报告391例马来丝虫病用海群生短程疗法,治毕三天、半年、一年、一年半、二年及三年半的疗效观察结果。其中1.5克顿服者171例;二天总量2克者78例;二天总量3克者142例。(2)1.5克组治后观察二周淋巴系统反应的发生率为60.8%。其他组治毕3～5天淋巴系统反应的发生率高低与剂量大小成正比。(3)1.5克组治毕三天微丝蚴阴转率为39.2%,较2克和3克组的55.7%及65.7%有显著差别,但在治后半年及一年时三组的微丝蚴阴转率相似。三组于治毕三天、半年、一年复查,阳性者微丝蚴减少率均在95%以上。但一年半以后无论阴转率或减少率三组均逐渐降低,这可能是由于重复感染的缘故。(4)治后微丝蚴阴转率的高低与治前微丝蚴的多寡成反比,治后阳性者残存条数的多寡则与治前微丝蚴的多寡成正比。(5)海群生1.5克顿服治疗马来丝虫病的方法是值得推荐的,但如治前微丝蚴的条数较多,则有必要考虑增大剂量延长疗程或反复查治。
(1) This article reports 391 cases of malay filariasis using sea group short-course therapy, complete three days, six months, a year, a year and a half, two and three and a half of the efficacy of the observation. Among them, 171 cases were treated with 1.5 grams of Dayton, 78 cases with 2 grams in two days and 142 cases with 3 grams in two days. (2) The incidence of two-week lymphatic system reaction in 1.5g group was 60.8%. The other group completed 3 to 5 days the incidence of lymphatic system is proportional to the size and dose size. (3) The negative conversion rate of microfilariae was 39.2% in 1.5g group compared with 55.7% and 65.7% in 2g and 3g groups, but the difference was not significant Silkworm negative conversion rate is similar. Three groups in the treatment of three days, six months, a year review, the positive rate of microfilariae were more than 95%. However, after one and a half years, no matter the rate of negative conversion or the rate of decrease, all three groups gradually decreased, which may be due to repeated infections. (4) After the treatment of microfilaria laryngeal negative conversion rate and the number of pre-treatment microfilaria is inversely proportional to the number of surviving positive number is proportional to the number of pre-treatment microfilariae. (5) Method of treatment of malayian filariasis by seaquot 1.5g Dayton clothing is recommended, but if the number of microfilariae before treatment is more, then it is necessary to consider increasing the dose to extend the course of treatment or repeated check.