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甲硝唑漱口液用于防治厌氧菌口腔感染。制剂中常加入0．03％羟苯乙酯作抑菌剂，用紫外法测定含量产生干扰，使结果偏高。为了消除干扰，制剂规范用双波长法测定。现报道用正交函数分光光度法测定其含量。按处方比例称量取甲硝哇、羟苯乙酯和薄荷附适量，以0．lmol／l一盐酸分别
Metronidazole mouthwash for the prevention and treatment of anaerobic oral infections. 0.03% Hydroxy-phenethyl is often added as a bacteriostatic agent in the preparation, and the content is determined by the ultraviolet method to interfere with the result, resulting in a high result. In order to eliminate interference, formulation specifications using dual wavelength method. Is reported using orthogonal function spectrophotometry determination of its content. Weigh the prescription proportion of metronidazole wow, hydroxyphenylacetate and mint appropriate amount to 0. lmol / l a hydrochloric acid, respectively