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本文总结了日本国立癌中心六年间治疗过的206例成人恶性淋巴瘤的疗效,并复习了最近各国有关的代表性文献,对当前该类疾患的治疗作了系统介绍。大量剖腹探查的结果证实,恶性淋巴瘤和白血病一样,是一种全身性疾患。因而,化疗应为其主要治疗手段。化疗的目标,可说是消灭所有瘤细胞。自采用多种有效抗癌药物联合使用的所谓“诱导缓解疗法”,以消灭残存瘤细胞为目的的“强化疗法”,及为保证前两种疗法安全进行而配合的“支持疗法”以后,就出现了缓解率上升,缓解期和生存期延长,长期生存病例增多的结果。
This article summarizes the curative effects of 206 adult malignant lymphomas treated by the National Cancer Center in Japan in the past six years and reviews the recent relevant literature in various countries and systematically introduces the current treatment of such diseases. The results of a large number of laparotomy confirmed that, like leukemia, malignant lymphoma is a systemic disorder. Therefore, chemotherapy should be its main treatment. The goal of chemotherapy is to eliminate all the tumor cells. Since the so-called “induction of remission therapy”, which is a combination of various effective anti-cancer drugs, “intensive chemotherapy” for the purpose of eliminating residual tumor cells and “supportive therapy” to ensure the safety of the first two therapies, Appear increased response rate, remission and prolonged survival, the results of long-term survival cases.