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目的探讨不典型胸痛伴2型糖尿病患者冠状动脉造影特点。方法选择我院2005年9月-2011年6月因不典型胸痛行冠脉造影患者418例;其中2型糖尿病患者70例(A组),非2型糖尿病患者348例(B组)。回顾性观察不典型胸痛伴2型糖尿病患者冠心病阳性率及冠脉造影特点。结果 A组冠心病发生率明显高于B组(P<0.01);A组单支病变比B组明显少(P<0.01);A组双支病变比B组明显多(P<0.01);A组三支病变比B组明显多(P<0.01);且A组弥漫性病变、分叉病变、开口病变与小血管病变等也显著增高,其差异有统计学意义(P<0.01)。结论不典型胸痛伴2型糖尿病患者冠心病发生率高,以多支病变、弥漫性病变、分叉病变、开口病变与小血管病变为特征。因此,2型糖尿病的早期发现、早期治疗及糖尿病患者严格积极地控制血糖,有助于糖尿病心血管并发症的预防。
Objective To investigate the characteristics of coronary angiography in patients with atypical chest pain and type 2 diabetes mellitus. Methods 418 cases of coronary angiography due to atypical chest pain were selected from September 2005 to June 2011 in our hospital. Among them, 70 cases were type 2 diabetes mellitus (group A) and 348 cases were non-type 2 diabetes mellitus (group B). Retrospective observation of atypical chest pain with type 2 diabetes patients with coronary heart disease positive rate and coronary angiography features. Results The incidence of coronary heart disease in group A was significantly higher than that in group B (P <0.01). The single vessel lesion in group A was less than that in group B (P <0.01). The double vessel lesion in group A was significantly more than that in group B (P <0.01). A group of three lesions was significantly more than the B group (P <0.01); and group A diffuse lesions, bifurcation lesions, open lesions and small vessel lesions were also significantly increased, the difference was statistically significant (P <0.01). Conclusions The incidence of coronary heart disease in patients with atypical chest pain and type 2 diabetes mellitus is high and is characterized by multiple lesions, diffuse lesions, bifurcation lesions, open lesions and small vessel lesions. Therefore, the early detection of type 2 diabetes, early treatment and diabetes patients strictly and strictly control blood sugar, contribute to the prevention of diabetic cardiovascular complications.