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目的分析浙江省2010年8月龄~4岁儿童麻疹腮腺炎联合减毒活疫苗(MM)强化免疫(SIA)效果,为流行性腮腺炎(流腮)免疫策略调整提供依据。方法采用描述性方法分析疾病监测信息报告管理系统报告的流腮监测数据。结果浙江省流腮年均报告发病率由SIA前(2004~2010年)的47/10万下降至SIA后(2011~2014年)的28/10万;2011~2014年报告发病率持续下降。年均流腮暴发起数由SIA前的38起下降至SIA后的8起;SIA后5~9岁年龄组(SIA对象)报告发病率由流腮纳入免疫规划(EPI)前(2004~2007年)的418/10万下降至275/10万,但该年龄组报告发病率仍最高。结论 MM SIA对流腮防控效果明显,建议全国范围内推行2剂次含流腮成分疫苗的免疫策略,在入小学前完成第2剂次接种。
Objective To analyze the effect of intensive immunization (SIA) on measles mumps combined with measles mumps in children aged 8 months to 4 years in Zhejiang province in 2010, which provides the basis for the immunization strategy adjustment for mumps. Methods Descriptive methods were used to analyze mumps monitoring data reported by the CDMIS. Results The annual reported incidence of cheeks in Zhejiang province decreased from 47/10 million in pre-SIA (2004-2010) to 28/10 in post-SIA (2011-2014). The reported incidence in 2011-2014 continued to decrease. The average number of annual mean bursal gynecological strikes decreased from 38 before SIA to 8 after SIA. The incidence of 5 to 9-year-old patients (SIA subjects) after SIA was reported by preemptive immunization programs (2004-2007) Year) fell to 418/10 million to 418/10 million, but the highest reported incidence in this age group. Conclusion MM SIA has obvious effect on preventing and controlling gout. It is recommended that a 2-dose immunization strategy should be implemented nationwide to achieve the second dose vaccination before entering primary school.