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目的探讨清肺汤与利巴韦林联合用药对小儿病毒性肺炎的临床疗效。方法随机将在我院接受治疗的76例小儿病毒性肺炎患儿分为对照组和联合治疗组各38例,对照组采用单纯的利巴韦林治疗,联合治疗组在对照组的基础上加用清肺汤治疗,观察两组患儿治疗后的临床症状改善情况和总有效率作为药物疗效评价指标。结果联合治疗组的发热、咳喘及肺啰音的平均消失时间分别为2.5±1.7d、3.6±1.4d、4.5±2.3d,总有效率为85.5%,与对照组患者3.6±1.6d、4.7±2.4d、6.8±1.1d,总有效率为72.6%相比较,各项指标均具有显著性差异(P<0.05或P<0.01)。结论清肺汤与利巴韦林联合用药对小儿病毒性肺炎具有显著的临床疗效,其效果优于单纯的利巴韦林治疗,此法在临床具有推广价值。
Objective To investigate the clinical effect of qingfei decoction combined with ribavirin on pediatric viral pneumonia. Methods A total of 76 cases of children with viral pneumonia treated in our hospital were randomly divided into control group and combination therapy group, 38 cases in each group. The control group was treated with ribavirin alone. The combination therapy group was based on the control group Qingfei decoction treatment, observation of two groups of children after treatment to improve the clinical symptoms and the total effective rate as a drug evaluation index. Results The average disappearance time of fever, cough and pulmonary rales were 2.5 ± 1.7d, 3.6 ± 1.4d and 4.5 ± 2.3d respectively in the combined treatment group, with a total effective rate of 85.5% and 3.6 ± 1.6d in the control group, 4.7 ± 2.4d, 6.8 ± 1.1d, the total effective rate was 72.6%, all the indexes had significant difference (P <0.05 or P <0.01). Conclusion Qingfei decoction combined with ribavirin has significant clinical curative effect on pediatric viral pneumonia and its effect is better than that of ribavirin alone. This method has the popularization value in clinic.