报告１４例肾结石合并肾鳞状上皮细胞癌。诊断采用静脉造影和逆行造影、Ｂ超、ＣＴ、肾γ－闪烁照相扫描等方法。１０例行肾切除术，２例未获成功，另外２例由于肾功能严重受损而行保留肾脏取石术，随访５年仅存活３例。认为肾结石合并肾鳞状上皮细胞癌与结石长期慢性刺激使肾盂移行上皮发生鳞状上皮化生有关，同时结石合并感染致肾功能严重受损或肾功能丧失也是致癌的潜在因素。 Report of 14 cases of renal calculi combined with renal squamous cell carcinoma. Diagnosis using venography and retrograde angiography, B ultrasound, CT, renal γ-scintigraphy scanning and other methods. Nephrectomy was performed in 10 cases. Two cases were unsuccessful. The other two cases were retained with renal lithotomy because of severe renal dysfunction. Only 3 cases survived 5 years. It is considered that kidney stones associated with squamous cell carcinoma of the kidney and long-term chronic stone irritation cause metaplastic squamous metaplasia in the renal pelvis transitional epithelium. At the same time, severe kidney damage or renal dysfunction caused by stones combined infection is also a potential carcinogen.