帕金森病(PD)是以黑质多巴胺能神经元变性为特征的中枢退行性疾病。研究表明氧化应激反应对PD神经元死亡起促进作用,减少氧化应激可阻止疾病的恶化。本文简要综述了氧化应激在PD发病中的作用,及现有用于PD的抗氧化药物,如多巴胺受体激动剂、还原型谷胱甘肽、人参皂苷Rg1、维生素E和银杏叶提取物的概况。 Parkinson’s disease (PD) is a central degenerative disease characterized by degeneration of substantia nigra dopaminergic neurons. Studies have shown that oxidative stress can promote the death of PD neurons and reduce oxidative stress to prevent the disease from deteriorating. This article briefly reviews the role of oxidative stress in the pathogenesis of PD, as well as the existing antioxidant drugs used in PD such as dopamine receptor agonists, reduced glutathione, ginsenoside Rg1, vitamin E and Ginkgo Biloba extract General situation.