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本文报道腹腔注射法进行卫氏肺吸虫对狗实验感染的成功,囊蚴在狗体腹腔脱囊后迁移过程可见横膈膜上虫道、胸膜穿孔与肺脏浅表囊肿。剖囊结果查有成熟虫体和虫卵及组织切片的肺吸虫病理变化。其平均虫体检出率(39.27％)显较经口饲喂法(19％)为高,成虫发育率随感染后时间增长而升高,2～5个月间的差异性非常显著,超过5个月者则否。虫体在雌雄狗内分布均以肺脏最多,胸腔次之,腹腔最少。该法简单易行可供研究工作参考。
In this paper, we report the success of experimental infection with Paragonimus westermani in dogs by intraperitoneal injection, and the larvae of the metacercariae and pleura perforation and the superficial lung cysts in the migrating process of the metacercaria were observed after the cercaria larvae were removed. The results of dissection were examined for the pathological changes of paragonimiasis in mature parasites and eggs and tissue sections. The average detection rate of worms (39.27%) was higher than that of oral feeding (19%). The rate of adult development increased with time after infection, and the difference between 2 and 5 months was very significant 5 months are not. The parasites in the male and female dogs were most distributed in the lungs, followed by the chest, abdominal at least. The method is simple and easy for reference for research work.