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放疗是头颈部癌常用的治疗方法,有时与手术或化疗一起进行,放疗的副反应之一是味觉损害,接受放疗的头颈癌患者约75%都有味觉障碍,93%患者苦于长期唾液分泌减少,虽然都知道是放射线造成味觉损害,但很少有对其损害实态的详细报告,对放射损伤的继发性味觉障碍的治疗,几乎持续于束手无策的状态。本文收集近期文献,对放射损伤性味觉障碍的状况进行综述。 1 癌与味觉障碍据Dewys和Wslters等报告,患消化道恶性肿瘤或乳腺癌治疗前约20%患者的甜味觉阈升高,并且阈值随肿瘤的发展而增高,推测由于锌或烟酸缺乏所致,或由产生于肿瘤的某些物质引起。据报告头颈癌患者的阈值是苦味阈,
Radiotherapy is a commonly used treatment for head and neck cancer and sometimes is performed with surgery or chemotherapy. One of the side effects of radiation therapy is taste impairment. About 75% of patients with head and neck cancer undergoing radiotherapy have taste disorders and 93% suffer from long-term salivary secretion Reduced, although both know that it is taste damage caused by radiation, there is very little report on the actual state of damage to it, and the treatment of secondary damage to taste and taste of radiation damage lasted almost at a loss. This article collects recent literature to review the status of radiation-induced impairment of taste. 1 cancer and taste disorders According to Dewys and Wslters other reports, about 20% of patients with gastrointestinal malignancies or breast cancer before the treatment of sweet taste threshold increased, and the threshold with the development of tumors increased, presumably due to lack of zinc or niacin Caused, or caused by certain substances that arise from tumors. The threshold for head and neck cancer patients is reported to be the bitterness threshold,