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目的观察右美托咪定腰硬麻醉在子宫肌瘤切除术中的临床镇静效果。方法 80例子宫肌瘤患者,随机分为对照组和观察组,各40例。两组均采取腰硬麻醉方式,对照组患者给予丙泊酚,观察组患者施以右美托咪定,对比两组患者术后Ramsay评分、心率(HR)、BIS。结果手术后,观察组患者Ramsay评分为(4.94±0.31)分,对照组为(2.54±0.12)分,观察组患者镇静效果优于对照组(P<0.05);观察组患者HR为(63.25±5.21)次/min,对照组为(72.63±5.13)次/min;观察组患者BIS为(62.41±6.78)分,对照组为(85.11±9.51)分。比较差异具有统计学意义(P<0.05)。结论在子宫肌瘤切除术中运用右美托咪定腰硬麻醉,有利于提升镇静效果,缓解患者术后痛苦,具有较大临床推广价值。
Objective To observe the clinical sedation effect of dexmedetomidine and lumbar spinal anesthesia in myomectomy. Methods 80 patients with uterine fibroids were randomly divided into control group and observation group, 40 cases each. The patients in the control group were given propofol. The patients in the observation group were given dexmedetomidine. Ramsay score, heart rate (HR) and BIS were compared between the two groups. Results After operation, the Ramsay score was (4.94 ± 0.31) in the observation group and (2.54 ± 0.12) in the control group, and the observation group had better sedation than the control group (P <0.05). HR in the observation group was (63.25 ± 5.21) times / min, and the control group was (72.63 ± 5.13) times / min. The BIS in the observation group was (62.41 ± 6.78) points and that in the control group was (85.11 ± 9.51) points. The difference was statistically significant (P <0.05). Conclusion The use of dexmedetomidine in the myomectomy for lumbar epidural anesthesia is conducive to enhancing the sedation effect and alleviating the postoperative pain in patients with great clinical value.